| Continued? | Issue | Team-up | Villain | Notes |
|---|---|---|---|---|
| Yes | 1 | S/T | Sandman | |
| 2 | S/T | Annihulus/Frightful Four | ||
| Yes | 3 | S/T | Morbius | |
| 4 | S/X-Men | |||
| Yes | 5 | S/Vision | Puppet Master | |
| 6 | S/Thing | Puppet Master/Mad Thinker | ||
| 7 | S/Thor | Kryllk | Avengers Mansion cameo | |
| 8 | S/The Cat | Man-Killer | ||
| Yes | 9 | S/Iron Man | Zarrko/Kang | Avengers Mansion |
| 10 | S/Thor | |||
| 11 | S/Inhumans | |||
| 12 | S/Werewolf (J. Russell) | Moondark | ||
| 13 | S/Captain America | Grey Gargoyle | ||
| 14 | S/Sub-Mariner | Tiger Shark/Dorcas/Men-Fish | ||
| 15 | S/Ghost Rider | The Orb | ||
| Yes | 16 | S/Captain Marvel | Basilisk | |
| 17 | S/Mr. Fantastic | Mole Man | ||
| 18 | T/Hulk | Blastaar | ||
| Yes | 19 | S/Ka-Zar | Stegron, the Dinosaur Man | |
| 20 | S/Black Panther | |||
| 21 | S/Dr. Strange | Xandu | ||
| 22 | S/Hawkeye | Quasimodo | ||
| 23 | T/Iceman | Equinox | ||
| 24 | S/Brother Voodoo | Moondog | ||
| 25 | S/Daredevil | Unholy Trio (Bird-Man, Cat-Man, Ape-Man) | ||
| 26 | T/Thor | Lava Men | ||
| 27 | S/Hulk | Chameleon | ||
| 28 | S/Hercules | City-Stealers | ||
| 29 | T/Iron Man | Infinitus | ||
| 30 | S/Falcon | Midas | ||
| 31 | S/Iron Fist | Drom, the Backwards Man | ||
| 32 | T/Son of Satan | Dryminextes | ||
| Yes | 33 | S/Nighthawk | Meteor Man | |
| 34 | S/Valkyrie | |||
| 35 | T/Dr. Strange | Jeremiah | ||
| Yes | 36 | S/Frankenstein Monster | Monster Maker | |
| 37 | S/Man-Wolf | |||
| 38 | S/Beast | Griffin | ||
| Yes | 39 | S/T | Crime-Master/Big Man/Sandman/Enforcers | |
| 40 | S/Sons of the Tiger | |||
| Yes | 41 | S/Scarlet Witch | Cotton Mather/Dark Rider | |
| 42 | S/Vision | |||
| 43 | S/Dr. Doom | |||
| 44 | S/Moondragon | |||
| 45 | S/Killraven | Martians | ||
| 46 | S/Deathlok | |||
| 47 | S/Thing | Basilisk | crossover w/Marvel Two-in-one 17 | |
| Yes | 48 | S/Iron Man | The Wraith | |
| 49 | ||||
| 50 | S/Dr. Strange | |||
| 51 | S/Iron Man | |||
| 52 | S/Captain America | Batroc/Demon | ||
| Yes | Ann. 1 | S/X-Men | Brahma, Mara, Yama Dharma, Kali, Agni, Shiva, Vishnu, Ratri | |
| 53 | S/Hulk | Woodgod | ||
| 54 | S/Hulk | Woodgod/US Army | ||
| 55 | S/Warlock | The Stranger | ||
| 56 | S/Daredevil | Blizzard/Electro | ||
| 57 | S/Black Widow | Silver Samurai | ||
| 58 | S/Ghost Rider | Trapster | ||
| Yes | 59 | S/Yellowjacket/Wasp | Equinox | |
| 60 | S/Wasp | |||
| Yes | 61 | S/Human Torch | Super-Skrull | |
| 62 | S/Ms. Marvel | |||
| Yes | 63 | S/Iron Fist | Steel Serpent | |
| 64 | S/Daughters of the Dragon | |||
| Yes | 65 | S/Captain Britain | Arcade | |
| 66 | ||||
| 67 | S/Tigra | Kraven the Hunter | ||
| 68 | S/Man-Thing | D'Spayre | ||
| Yes | 69 | S/Havok | Living Monolith | |
| 70 | S/Thor | |||
| 71 | S/Falcon | Plantman | Captain America cameo | |
| 72 | S/Iron Man | Whiplash | ||
| 73 | S/Daredevil | The Owl | ||
| 74 | S/Not-Ready-for-Prime-Time-Players | Silver Samurai | ||
| 75 | S/Power Man (Luke Cage) | fire | ||
| Yes | 76 | S/Dr. Strange | Silver Dagger | |
| 77 | S/Ms. Marvel | |||
| 78 | S/Wonderman | Griffin | ||
| 79 | S/Red Sonja | Kulan Gath | ||
| Yes | 80 | S/Dr. Strange/Clea | Silver Dagger follow-up | |
| 81 | S/Satana | death of Satana | ||
| Yes | 82 | S/Black Widow | Boomerang/Silver Samurai/Viper | |
| 83 | S/Nick Fury | |||
| 84 | S/Shang-Chi | |||
| 85 | S/Black Widow/Nick Fury/Shang-Chi | |||
| Ann. 2 | S/Hulk | some Russian guy | ||
| 86 | S/Guardians of the Galaxy | Hammer & Anvil | ||
| 87 | S/Black Panther | Hellrazor | ||
| 88 | S/Invisible Girl | Boss Morgan | Hank & Jan Pym cameo | |
| 89 | S/Nightcrawler | Cutthroat | ||
| 90 | S/Beast | Killer Strike/Modular Man | ||
| 91 | S/Ghost Rider | Moondark | ||
| 92 | S/Hawkeye | Mr. Fear | ||
| Yes | 93 | S/Werewolf (J. Russell) | Tatterdemalion | |
| 94 | S/The Shroud | Dansen Macabre | ||
| 95 | S/Mockingbird | Delanden and his Satan Claw! | ||
| 96 | S/Howard the Duck | Staus Quo | ||
| 97 | Hulk/Spider-Woman | Dr. Benway | ||
| Ann. 3 | Hulk/Powerman/Iron First (with Machine Man) | Nightshade | Spider-Man cameo | |
| 98 | S/Black Widow | The Owl | ||
| 99 | S/Machine Man | Baron Brimstone/Sandman | ||
| 100 | S/Fantastic Four | Karma | ||
| 100b | Storm/Black Panther | Andreas DeReyter | ||
| 101 | S/Nighthawk | |||
| 102 | S/Doc Samson | Rhino/Delilah | ||
| 103 | S/Ant-Man | Taskmaster | followup to Avengers 196 | |
| 104 | Hulk/Ka-Zar | Modok | ||
| 105 | Hulk/Powerman/Iron First | |||
| 106 | S/Captain America | Scorpion | ||
| 107 | S/She-Hulk | Man-Killer | ||
| Yes | 108 | S/Paladin | Thermo the Thermatronic Man | |
| 109 | S/Dazzler | |||
| Ann. 4 | S/Daredevil/Moon Knight/Powerman/Iron Fist | Killgrave the Purple Man | ||
| 110 | S/Iron Man | Magma | ||
| Yes | 111 | S/Devil-Slayer | Serpent Men | Defenders cameo |
| 112 | S/King Kull | Ju-Lak | ||
| 113 | S/Quasar | Lightmaster | ||
| 114 | S/Falcon | Stone-Face | ||
| Yes | 115 | S/Thor | Meru the Mind-Bender | |
| 116 | S/Valkyrie | Meru the Mind-Bender/Dalia the Shape-Changer | ||
| Yes | 117 | S/Wolverine | Professor Power | |
| 118 | S/Professor X | The Fixer/Mentallo | ||
| 119 | S/Gargoyle | |||
| 120 | S/Dominic Fortune | Turner D. Century | ||
| 121 | S/T | Speed Demon | Leap Frog appearance | |
| Yes | 122 | S/Man-Thing | Ian Fate | |
| 123 | S/Daredevil | Solarr | ||
| 124 | S/Beast | Professor Power | ||
| 125 | S/Tigra | Zabo | ||
| 125b | Dr. Stange/Scarlet Witch | Beliath | ||
| 126 | Powerman/Son of Satan | Sons of Satannish | ||
| 126b | S/Hulk | |||
| 127 | S/The Watcher | Special Christmas Issue | ||
| 128 | S/Captain America | Vermin | Photo cover | |
| Yes | 129 | S/Vision | Alpha | |
| 130 | S/Scarlet Witch | Necrodamus | ||
| 131 | S/Frog-Man | White Rabbit | ||
| Yes | 132 | S/Mr. Fantastic | Everyman | |
| 133 | S/Fantastic Four | Dr. Faustus | ||
| 134 | S/Jack-of-Hearts | |||
| 135 | S/Kitty Pryde | Morlocks | ||
| 136 | S/Wonder Man | Mauler | ||
| 149 | S/Cannonball | The Incandescent Man | ||
| 150 | S/X-Men | Juggernaut |
(Becomes Web of Spider-Man)